Intestinal Nematode and Cestode Treatment and Control: Dogs may be exposed to and can become infected with roundworms, whipworms, hookworms, and tapeworms throughout the year, regardless of season or climate. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product, as necessary. In areas where fleas are common year-round, monthly treatment with SENTINEL SPECTRUM Chews should continue the entire year without interruption. When switching from another heartworm preventative product to SENTINEL SPECTRUM Chews, the first dose of SENTINEL SPECTRUM Chews should be given within a month of the last dose of the former product.įlea Treatment and Prevention: Treatment with SENTINEL SPECTRUM Chews may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. SENTINEL SPECTRUM Chews may be administered year-round without interruption. Heartworm Prevention: SENTINEL SPECTRUM Chews should be administered at monthly intervals beginning within one month of the dog’s first seasonal exposure to mosquitoes and continuing until at least 6 months after the dog’s last seasonal exposure (see EFFECTIVENESS). If it is suspected that any of the dose has been lost, redosing is recommended. Care should be taken that the dog consumes the complete dose, and treated animals should be observed a few minutes after administration to ensure that no part of the dose is lost or rejected. Chewables may be broken into pieces and fed to dogs that normally swallow treats whole. The chewables should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. SENTINEL SPECTRUM Chews may be offered to the dog by hand or added to a small amount of dog food. To ensure adequate absorption, always administer SENTINEL SPECTRUM Chews to dogs immediately after or in conjunction with a normal meal. For heartworm prevention, give once monthly for at least 6 months after exposure to mosquitoes (see EFFECTIVENESS).Īdminister the appropriate combination of chewables SENTINEL SPECTRUM Chews should be administered orally, once every month, at the minimum dosage of 0.23 mg/lb (0.5 mg/kg) milbemycin oxime, 4.55 mg/lb (10 mg/kg) lufenuron, and 2.28 mg/lb (5 mg/kg) praziquantel.
SENTINEL SPECTRUM Chews are indicated for the prevention of heartworm disease caused by Dirofilaria immitis for the prevention and control of flea populations (Ctenocephalides felis) and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina), adult hookworm (Ancylostoma caninum), adult whipworm (Trichuris vulpis), and adult tapeworm (Dipylidium caninum, Taenia pisiformis, Echinococcus multilocularis and Echinococcus granulosus) infections in dogs and puppies two pounds of body weight or greater and six weeks of age and older. Praziquantel is an isoquinolone anthelmintic with the chemical name 2-(Cyclohexylcarbonyl)-1,2,3,6,7,-11b-hexahydro-4H-pyrazinoisoquinolin-4-one. Benzoylphenylurea compounds, including lufenuron, are classified as insect development inhibitors (IDIs). Lufenuron is a benzoylphenylurea derivative with the following chemical composition: N-2,6-difluorobenzamide (C 17H 8Cl 2F 8N 2O 3, MW 511.15). Milbemycin oxime is classified as a macrocyclic anthelmintic. Milbemycin oxime consists of the oxime derivatives of 5-didehydromilbemycins in the ratio of approximately 80% A 4 (C 32H 45NO 7, MW 555.71) and 20% A 3 (C 31H 43NO 7, MW 541.68). Each chewable flavored tablet is formulated to provide a minimum of 0.23 mg/pound (0.5 mg/kg) of milbemycin oxime, 4.55 mg/pound (10 mg/kg) of lufenuron, and 2.28 mg/pound (5 mg/kg) of praziquantel. SENTINEL ® SPECTRUM ® Chews are available in four strengths in color-coded packages for oral administration to dogs and puppies according to their weight. praziquantel) Sentinel Spectrum Chews Cautionįederal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.
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